Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
Fenofibrate is hydrolyzed in vivo to its active metabolite fenofibric acid that binds to and activates peroxisome proliferator activated receptor alpha (PPARalpha), resulting in reduction of total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) but increase of HDL cholesterol.

 

Product Name Fenofibrate
CAS Number 49562-28-9
Therapeutic Class Antilipemic Agents, hypercholesterolemia, dyslipidemia, hypertriglyceridemia 
Dosage Form Oral Tablet
Availability Commercial
Regulatory Status USDMF, CEP, JDMF, CADMF