Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
Fenofibrate is hydrolyzed in vivo to its active metabolite fenofibric acid that binds to and activates peroxisome proliferator activated receptor alpha (PPARalpha), resulting in reduction of total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) but increase of HDL cholesterol.
Product Name |
Fenofibrate |
CAS Number |
49562-28-9 |
Therapeutic Class |
Antilipemic Agents, hypercholesterolemia, dyslipidemia, hypertriglyceridemia |
Dosage Form |
Oral Tablet |
Availability |
Commercial |
Regulatory Status |
USDMF, CEP, JDMF, CADMF |