Ganaxolone, a positive allosteric modulator of GABAa and synthetic analog of allopregnanolone, acts on a well-characterized synaptic and extrasynaptic target known for antiepileptic (anti-seizure), anxiolytic (anti-anxiety), and anti-depressive activity.
Marinus is developing three different convenient dose forms of ganaxolone—IV, capsule, and liquid—to maximize the therapeutic reach to adult and pediatric patients in both acute and chronic care settings.


Product Name Ganaxolone
CAS Number 38398-32-2
Therapeutic Class Neuroactive Steroid
Dosage Form Oral capsule and liquid, Injection
Availability Under Evaluation
Regulatory Status