Palonosetron is a carbazole derivative and a selective serotonin receptor antagonist with antiemetic activity.
Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting.

Product Name Palonosetron Hydrochloride
CAS Number 135729-62-3
Therapeutic Class Serotonin (5-HT3) receptor antagonist, Antiemetic 
Dosage Form Solution for Injection, Oral Capsule
Availability Commercial
Regulatory Status USDMF, EDMF, JDMF